The Spanish League leaders slipped to a 2-0 defeat at home to Real Mallorca.
Real were pushing hard for the victory they needed to move back on top of the Primera Liga standings.
Depor's two Barcelona-born players scored in each half to secure victory at the Nou Camp.
They joined Valencia and Stuttgart on top of their respective divisions after weekend action in Europe's main leagues.
The victory sent Valencia to the top of the Spanish league.
Barcelona surrendered lead to arch-rivals Real Madrid after they were held to a 1-1 draw at home to Real Betis.
Striker Raul scored after 24 minutes and late in the second half Robinho broke away to seal the side's third win in a row.
Real Madrid drew 1-1 at home with local rivals Getafe in the Bernabeu.
Sevilla knocked Barcelona off the top of the Primera Liga after goals from Frederic Kanoute and Adriano Correia earned a 2-0 home win over Osasuna on Sunday.
A Ronaldinho double and solo goal from Lionel Messi gave Barcelona a 3-1 home win against high-flying Sevilla.
Coach Laurent Blanc parted ways with Paris St Germain, putting pen to paper on a 22-million-euro ($25 million) severance deal.
Real Madrid's Karim Benzema, who won the 2022 Ballon d'Or award, is also in the shortlist.
Real Madrid's France forward Karim Benzema won the 2022 Ballon d'Or award for the best men's player in the world on Monday, while Barcelona's Spain midfielder Alexia Putellas won the women's award for a second time.
As Leicester City celebrates its unexpected title triumph, Bikash Mohapatra/Rediff.com lists similar success stories across Europe's top leagues.
Spanish soccer's 'El Clasico' encounters between Barcelona and Real Madrid will happen in December and April, two of the most anticipated games of the 2016-17 Primera Division season whose fixtures were announced on Friday. Defending champions Barca host Real on Dec. 4 at the Camp Nou. The reverse fixture will take place on April 23, at the Bernabeu stadium, the Spanish Football Federation (RFEF) confirmed after the draw. As the La Liga season kicks off, Barca will begin their title defence at home to Real Betis on Aug. 21.
As we sit at home and miss live action, the wondrous phenomenon of sport has delivered so many past glories that we will probably never run out of things to see, recalls Dhruv Munjal.
Angel di Maria's move from Real Madrid to Old Trafford was such a disaster that Manchester United was more than willing to incur losses of more than 15 million pounds on their investment. Bikash Mohapatra/Rediff.com looks at the Argentina star's nightmare year at the 'Theatre of Dreams'.
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